BettermeRx vs Enhance MD: NAD+ Therapy Compared
BettermeRx starts at shown after free evaluation and offers injection, nasal spray & liposomal oral, while Enhance MD starts at wafers $84/mo; injection $169/mo with injection + sublingual wafer. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.

BettermeRx
Three NAD+ formats — injection, nasal spray, and liposomal. Flat pricing, no hidden fees.
Visit BettermeRx →Enhance MD
Injections $169–$199/mo or needle-free sublingual wafers $84–$99/mo. Physician oversight included.
Visit Enhance MD →| Feature | BettermeRx | Enhance MD |
|---|---|---|
| Editorial score | 9.72 / 10 | 8.51 / 10 |
| Starting price | Shown after free evaluation | Wafers $84/mo; injection $169/mo |
| Renewal / ongoing | Flat pricing, no increases | Wafers $84–$99; injection $169–$199 |
| Delivery formats | Injection, nasal spray & liposomal oral | Injection + sublingual wafer |
| Dose strengths | Injection 500/1000mg; nasal 900mg | Per physician protocol |
| Shipping | Free UPS/FedEx | Included |
| Membership / fees | None | None |
| Guarantee | — | Refund if ineligible |
| Best for | People who want to choose between injection, nasal spray, or liposomal NAD+ with flat, no-surprise pricing | People weighing injectable NAD+ against a needle-free sublingual wafer with full price transparency |
Where BettermeRx stands out
- + More delivery formats — injection, nasal spray & liposomal oral
- + Higher editorial score (9.72 vs 8.51)
Where Enhance MD stands out
- + Lower entry price — Wafers $84/mo; injection $169/mo
- + Backed by a refund if ineligible
- + Pricing shown upfront, before you start intake
Pros & cons, side by side
BettermeRx
Pros
- + Widest format choice: injection, nasal spray, and liposomal oral
- + Flat, all-inclusive pricing with no hidden fees
- + Free UPS/FedEx shipping on every order
- + U.S. board-certified physician evaluation included
Cons
- − Your exact price is shown after a free online evaluation
- − Compounded NAD+ — not an FDA-approved finished product
Enhance MD
Pros
- + Needle-free sublingual wafer alternative to injections
- + Full published pricing matrix by commitment length
- + Provider check-ins, messaging, and cellular health lab tracking included
- + Full refund if found ineligible
Cons
- − Lowest prices require a 12-month prepaid commitment
- − No nasal spray option
The verdict: BettermeRx vs Enhance MD
In our editorial ranking, BettermeRx places higher (#4 vs #13), making it the default pick for most readers — it's best for people who want to choose between injection, nasal spray, or liposomal NAD+ with flat, no-surprise pricing. That said, Enhance MD is the stronger choice for people weighing injectable NAD+ against a needle-free sublingual wafer with full price transparency. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.