Fridays vs Enhance MD: NAD+ Therapy Compared
Fridays starts at $179/mo (billed quarterly) and offers injection, nasal spray & oral liposomal, while Enhance MD starts at wafers $84/mo; injection $169/mo with injection + sublingual wafer. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
Fridays
NAD+ from $179/mo (billed quarterly). Injection, nasal spray, or oral liposomal.
Visit Fridays →
Enhance MD
Injections $169–$199/mo or needle-free sublingual wafers $84–$99/mo. Physician oversight included.
Visit Enhance MD →| Feature | Fridays | Enhance MD |
|---|---|---|
| Editorial score | 9.43 / 10 | 8.51 / 10 |
| Starting price | $179/mo (billed quarterly) | Wafers $84/mo; injection $169/mo |
| Renewal / ongoing | Nasal & oral $229/mo | Wafers $84–$99; injection $169–$199 |
| Delivery formats | Injection, nasal spray & oral liposomal | Injection + sublingual wafer |
| Dose strengths | Oral 50/100/150mg daily; injection 3×/week | Per physician protocol |
| Shipping | Medication included | Included |
| Membership / fees | None | None |
| Guarantee | — | Refund if ineligible |
| Best for | People wanting personalized NAD+ with a choice of injection, nasal spray, or oral delivery | People weighing injectable NAD+ against a needle-free sublingual wafer with full price transparency |
Where Fridays stands out
- + More delivery formats — injection, nasal spray & oral liposomal
- + Higher editorial score (9.43 vs 8.51)
Where Enhance MD stands out
- + Lower entry price — Wafers $84/mo; injection $169/mo
- + Backed by a refund if ineligible
Pros & cons, side by side
Fridays
Pros
- + One of the few providers offering injection, nasal spray, AND oral liposomal NAD+
- + Personalized protocol for your goals
- + Established trusted brand
Cons
- − Billed quarterly rather than month-to-month
- − Not available in all states
Enhance MD
Pros
- + Needle-free sublingual wafer alternative to injections
- + Full published pricing matrix by commitment length
- + Provider check-ins, messaging, and cellular health lab tracking included
- + Full refund if found ineligible
Cons
- − Lowest prices require a 12-month prepaid commitment
- − No nasal spray option
The verdict: Fridays vs Enhance MD
In our editorial ranking, Fridays places higher (#8 vs #13), making it the default pick for most readers — it's best for people wanting personalized NAD+ with a choice of injection, nasal spray, or oral delivery. That said, Enhance MD is the stronger choice for people weighing injectable NAD+ against a needle-free sublingual wafer with full price transparency. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.