DirectMeds vs ReadyRx: NAD+ Therapy Compared
DirectMeds starts at $99 first month (500mg) and offers injection, while ReadyRx starts at shown at intake with injection + nasal spray. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
DirectMeds
Save $100 first month — 500mg from $99, then $199. 250,000+ served. No subscription.
Visit DirectMeds →
ReadyRx
SPECIAL OFFER: $20 off with code RXUMA2026 — lab-tested injections & 4,500mg nasal spray
Visit ReadyRx →| Feature | DirectMeds | ReadyRx |
|---|---|---|
| Editorial score | 9.64 / 10 | 9.55 / 10 |
| Starting price | $99 first month (500mg) | Shown at intake |
| Renewal / ongoing | $199 (500mg) / $249 (1000mg) | Shown at intake |
| Delivery formats | Injection | Injection + nasal spray |
| Dose strengths | 500mg & 1000mg | Injection 500/1000mg; nasal 4,500mg |
| Shipping | Free 1–2 day | Free |
| Membership / fees | None — no subscription | None |
| Guarantee | Satisfaction guarantee | Third-party lab-tested |
| Best for | People who want exact upfront pricing and no forced subscription, reordering on their own schedule | People who want lab-tested NAD+ with a needle-free high-strength nasal option and physician messaging |
Where DirectMeds stands out
- + Lower entry price — $99 first month (500mg)
- + Pricing shown upfront, before you start intake
- + Higher editorial score (9.64 vs 9.55)
Where ReadyRx stands out
- + More delivery formats — injection + nasal spray
Pros & cons, side by side
DirectMeds
Pros
- + $100 off first month on the 500mg plan
- + Exact pricing shown upfront for both 500mg and 1000mg
- + No forced subscription — reorder manually when you want
- + 1:1 medical support with provider review within 24 hours
- + Free 1–2 day shipping included
Cons
- − Injection-only — no nasal or oral option
- − 1000mg plan renews at $249/mo
ReadyRx
Pros
- + Extra $20 savings with code RXUMA2026
- + Both injection and a high-strength 4,500mg nasal spray
- + Third-party lab-tested formulations
- + Unlimited physician messaging and free shipping
Cons
- − Live pricing is shown after you start the online intake
- − Not specialized exclusively in NAD+
The verdict: DirectMeds vs ReadyRx
In our editorial ranking, DirectMeds places higher (#5 vs #6), making it the default pick for most readers — it's best for people who want exact upfront pricing and no forced subscription, reordering on their own schedule. That said, ReadyRx is the stronger choice for people who want lab-tested NAD+ with a needle-free high-strength nasal option and physician messaging. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.