DirectMeds vs RenuviaRX: NAD+ Therapy Compared
DirectMeds starts at $99 first month (500mg) and offers injection, while RenuviaRX starts at $179 to start with injection. Below we line them up on price, delivery formats, dosing, shipping, and overall value so you can see which prescription NAD+ provider fits you best.
DirectMeds
Save $100 first month — 500mg from $99, then $199. 250,000+ served. No subscription.
Visit DirectMeds →
| Feature | DirectMeds | RenuviaRX |
|---|---|---|
| Editorial score | 9.64 / 10 | 9.55 / 10 |
| Starting price | $99 first month (500mg) | $179 to start |
| Renewal / ongoing | $199 (500mg) / $249 (1000mg) | $249/mo |
| Delivery formats | Injection | Injection |
| Dose strengths | 500mg & 1000mg | Per physician protocol |
| Shipping | Free 1–2 day | Free |
| Membership / fees | None — no subscription | None |
| Guarantee | Satisfaction guarantee | — |
| Best for | People who want exact upfront pricing and no forced subscription, reordering on their own schedule | People who want a board-certified physician to design their NAD+ protocol for both anti-aging skin benefits and improved energy and mental clarity. |
Where DirectMeds stands out
- + Lower entry price — $99 first month (500mg)
- + Backed by a satisfaction guarantee
- + Higher editorial score (9.64 vs 9.55)
Where RenuviaRX stands out
RenuviaRX is closely matched with DirectMeds on the headline metrics — the deciding factors come down to delivery format and the specifics below.
Pros & cons, side by side
DirectMeds
Pros
- + $100 off first month on the 500mg plan
- + Exact pricing shown upfront for both 500mg and 1000mg
- + No forced subscription — reorder manually when you want
- + 1:1 medical support with provider review within 24 hours
- + Free 1–2 day shipping included
Cons
- − Injection-only — no nasal or oral option
- − 1000mg plan renews at $249/mo
RenuviaRX
Pros
- + Board-certified physicians customize every treatment plan
- + Targets cellular skin repair alongside energy and mental clarity
- + No insurance needed — straightforward $179 starting price
- + Free shipping included on every order
- + Comprehensive approach: look younger and feel younger
Cons
- − Newer platform with a smaller patient base than legacy providers
- − Injection-only — no nasal or oral option
The verdict: DirectMeds vs RenuviaRX
In our editorial ranking, DirectMeds places higher (#5 vs #7), making it the default pick for most readers — it's best for people who want exact upfront pricing and no forced subscription, reordering on their own schedule. That said, RenuviaRX is the stronger choice for people who want a board-certified physician to design their NAD+ protocol for both anti-aging skin benefits and improved energy and mental clarity.. Both are prescription NAD+ services, so the right answer depends on the delivery format and price structure that match how you want to start.
More head-to-head comparisons
Pricing and product details were verified against each provider's official pages and may change — always confirm current terms on the provider's site. Rx required; a licensed provider determines whether NAD+ therapy is appropriate for you. We may earn a commission from links on this page, which never affects our rankings.